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Generic Name: Furosemide
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What is Generic Lasix and why is it prescribed?

Generic Lasix, furosemide is a potent diuretic (water pill). Generic Lasix for oral administration contains furosemide as the active ingredient and the following inactive ingredients:lactose monohydrate NF, magnesium stearate NF, starch NF, talc USP, and colloidal silicon dioxide NF. Chemically, it is 4-chloro-N-furfuryl-5-sulfamoylanthranilic acid. Furosemide is available as white tablets for oral administration in dosage strengths of 20 mg, 40 mg and 80 mg.

Generic Lasix is used in the treatment of high blood pressure and other conditions that require the elimination of excess fluid (water) from the body. These conditions include congestive heart failure, cirrhosis of the liver, and kidney disease. Generic Lasix is used to treat high blood pressure, Lasix is effective alone or in combination with other high blood pressure medications. Diuretics help your body produce and eliminate more urine, which helps lower blood pressure. Lasix is classified as a "loop diuretic" because of its point of action in the kidneys.

Furosemide is a white to off-white odorless crystalline powder. It is practically insoluble in water, sparingly soluble in alcohol, freely soluble in dilute alkali solutions and insoluble in dilute acids.

 

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Generic Lasix/ Furosemide is a "loop" diuretic that works within the kidneys to get rid of excess fluid and sodium (salt).

Generic Lasix (Furosemide) works by blocking the absorption of salt and fluid in the kidney tubules, thus causing increased excretion of water, sodium, and chloride into the urine to be expelled from the body (diuresis). The diuretic effect of Lasix (furosemide) can cause body water and electrolyte depletion. Therefore, careful medical supervision is necessary during treatment.

Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose schedule must be adjusted to the individual patient's needs. (See DOSAGE AND ADMINISTRATION.)

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Generic Lasix is as safe as Brand-Lasix. Generic-Lasix and Brand-Lasix have the same active ingredients. Generic-Lasix and Brand-Lasix have the same risks and benefits. Generic Lasix drug work in the same way and in the same amount of time as brand-Lasix drug.

 

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How does Generic Lasix work ?

Lasix furosemide is a "loop" diuretic that works within the kidneys to get rid of excess fluid and sodium (salt).

Lasix (furosemide) works by blocking the absorption of salt and fluid in the kidney tubules, thus causing increased excretion of water, sodium, and chloride into the urine to be expelled from the body (diuresis). The diuretic effect of Lasix (furosemide) can cause body water and electrolyte depletion. Therefore, careful medical supervision is necessary during treatment.

 

Generic Lasix Information

Generic Lasix or generically known as furosemide is a drug belonging to the drugs called diuretics. Diuretics or water pills are drugs that decrease the amount of fluids in the body by increasing the amounts of salt and water excreted in the urine.

Generic Lasix is indicated for patients who have are retaining unhealthy and dangerous amounts of fluids in the body that result to swelling. Among the patients with these kind of medical problem are those with congestive heart failures, livers disease and renal or kidney diseases.

Generic Lasix may also be indicated for purposes other than what is in this medicine guide.

Generic Lasix should be taken according to the prescription of your doctor. Never take Generic Lasix without fully understanding the instructions of your doctor. If your doctor's prescription is unclear to you, ask help from a medical authority such as nurse or pharmacist to verify the doctor's instructions for you.

A full glass of water should be used to down Generic Lasix into your stomach.

As Generic Lasix promotes excretion of fluids through the urine, it is advised that you take Generic Lasix earlier in the day to reduce nighttime urination unless otherwise prescribed by your doctor.

Take Generic Lasix regularly to greatly benefit from the effects of the drug.

Never abruptly stop taking Generic Lasix. Abrupt cessation of the medication could only make your condition worse. Termination of this medication should be under a doctor's supervision.

 

Generic Lasix food and drug interactions

If Lasix is taken with certain other drugs, the effects of either, could be increased, decreased, or altered. It is especially important to consult with your doctor before taking Lasix with any of the following: Aminoglycoside antibiotics such as Garamycin, Aspirin and other salicylates, Ethacrynic acid (Edecrin), Indomethacin (Indocin), Lithium (Lithonate), Norepinephrine (Levophed), Other high blood pressure medications such as Hytrin and Cardura, Sucralfate (Carafate).

 

Generic Lasix Special information

Special information on Lasix . If you are pregnant or breastfeeding, since the effects of Lasix during pregnancy have not been adequately studied, inform your doctor immediately.

Lasix appears in breast milk and could affect a nursing infant. If Lasix is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment is finished.

Most Important Fact about this Drug: Lasix acts quickly, usually within 1 hour. However, since blood pressure declines gradually, it may be several weeks before you get the full benefit of Lasix; and you must continue taking it even if you are feeling well. Lasix does not cure high blood pressure; it merely keeps it under control.

 

Generic Lasix Preparations

Generic Lasix Tablets and Oral Solution

Pediatric Patients: The usual initial dose of oral Generic Lasix in pediatric patients is 2 mg/kg body weight, given as a single dose of Generic Lasix. If the diuretic response is not satisfactory after the initial dose of Generic Lasix , dosage may be increased by 1 or 2 mg/kg no sooner than 6 to 8 hours after the previous dose of Generic Lasix . Doses greater than 6 mg/kg body weight are not recommended. For maintenance therapy in pediatric patients, the dose of Generic Lasix should be adjusted to the minimum effective level.

Generic Lasix FOR ADULTS

Fluid Retention
You will probably be started at a single dose of Generic Lasix of 20 mg to 80 mg. If needed, the same dose of Generic Lasix can be repeated 6 to 8 hours later, or the dose of Generic Lasix may be increased. Your doctor may raise the dosage by Generic Lasix 20 mg or Generic Lasix 40 mg with each successive administration-- each 6 to 8 hours after the previous dose of Generic Lasix - until the desired effect is achieved. This dosage is then taken once or twice daily thereafter. Your doctor should monitor you carefully using laboratory tests. The maximum daily dose is 600 mg. 

Generic Lasix in High Blood Pressure Treatment

The usual starting dose of Generic Lasix is 80 mg per day divided into 2 doses of Generic Lasix. Your doctor will adjust the dosage and may add other high blood pressure medications if Generic Lasix is not enough.

Generic Lasix FOR CHILDREN

The usual initial dose of Generic Lasix is 2 mg per 2.2 pounds of body weight given in a single oral dose of Generic Lasix. The doctor may increase subsequent doses of Generic Lasix by 1 to 2 mg per 2.2 pounds. Doses of Generic Lasix are spaced 6 to 8 hours apart. A child's dosage of Generic Lasix will be adjusted to the lowest needed to achieve maximum effect, and should not exceed 6 mg per 2.2 pounds.

If you miss a dose of Generic Lasix

Take the forgotten dose of Generic Lasix as soon as you remember. If it is almost time for your next dose of Generic Lasix, skip the missed dose of Generic Lasix and go back to your regular schedule. Never take 2 doses of Generic Lasix at the same time.

Generic Lasix Storage instructions

Keep Generic Lasix in the container it came in, tightly closed, and away from direct light. Store Generic Lasix at room temperature.

Preparations of Generic Lasix: Generic Lasix 20 mg, Generic Lasix 40 mg, Generic Lasix 80 mg.

 

Generic Lasix Indications and usage

Edema
Generic Lasix is indicated in adults and pediatric patients for the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Generic Lasix is particularly useful when an agent with greater diuretic potential is desired.

Hypertension
Generic Lasix may be used in adults for the treatment of hypertension (High Blood Pressure) alone or in combination with other antihypertensive agents. Hypertensive patients who cannot be adequately controlled with thiazides will probably also not be adequately controlled with Generic Lasix alone.

 

Generic Lasix Precautions

Take Generic Lasix exactly as prescribed by your doctor. Your doctor will adjust the dosages of Generic Lasix to meet your specific needs.

Excessive diuresis may cause dehydration and blood volume reduction with circulatory collapse and possibly vascular thrombosis and embolism, particularly in elderly patients. As with any effective diuretic, electrolyte depletion may occur during Generic Lasix therapy, especially in patients receiving higher doses of Generic Lasix and a restricted salt intake. Hypokalemia may develop with Generic Lasix, especially with brisk diuresis, inadequate oral electrolyte intake, when cirrhosis is present, or during concomitant use of corticosteroids or ACTH. Digitalis therapy may exaggerate metabolic effects of hypokalemia, especially myocardial effects.

All patients receiving Generic Lasix therapy should be observed for these signs or symptoms of fluid or electrolyte imbalance (hyponatremia, hypochloremic alkalosis, hypokalemia, hypomagnesemia or hypocalcemia): dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, arrhythmia, or gastrointestinal disturbances such as nausea and vomiting. Increases in blood glucose and alterations in glucose tolerance tests (with abnormalities of the fasting and 2-hour postprandial sugar) have been observed, and rarely, precipitation of diabetes mellitus has been reported.

Asymptomatic hyperuricemia can occur and gout may rarely be precipitated.

Patients allergic to sulfonamides may also be allergic to Generic Lasix. The possibility exists of exacerbation or activation of systemic lupus erythematosus.

As with many other drugs, patients should be observed regularly for the possible occurrence of blood dyscrasias, liver or kidney damage, or other idiosyncratic reactions.

 

Generic Lasix Interactions

Generic Lasix may increase the ototoxic potential of aminoglycoside antibiotics, especially in the presence of impaired renal function. Except in life-threatening situations, avoid this combination.

Generic Lasix should not be used concomitantly with ethacrynic acid because of the possibility of ototoxicity. Patients receiving high doses of salicylates concomitantly with Generic Lasix, as in rheumatic disease, may experience salicylate toxicity at lower doses because of competitive renal excretory sites.

Generic Lasix has a tendency to antagonize the skeletal muscle relaxing effect of tubocurarine and may potentiate the action of succinylcholine.

Lithium generally should not be given with diuretics because they reduce lithium's renal clearance and add a high risk of lithium toxicity.

Generic Lasix may add to or potentiate the therapeutic effect of other antihypertensive drugs. Potentiation occurs with ganglionic or peripheral adrenergic blocking drugs.

Generic Lasix may decrease arterial responsiveness to norepinephrine. However, norepinephrine may still be used effectively.

Simultaneous administration of sucralfate and Generic Lasix tablets may reduce the natriuretic and antihypertensive effects of Generic Lasix. Patients receiving both drugs should be observed closely to determine if the desired diuretic and/or antihypertensive effect of Generic Lasix is achieved. The intake of Generic Lasix and sucralfate should be separated by at least two hours.

One study in six subjects demonstrated that the combination of furosemide and acetylsalicylic acid temporarily reduced creatinine clearance in patients with chronic renal insufficiency. There are case reports of patients who developed increased BUN, serum creatinine and serum potassium levels, and weight gain when furosemide was used in conjunction with NSAIDs.

Literature reports indicate that coadministration of indomethacin may reduce the natriuretic and antihypertensive effects of Generic Lasix (furosemide) in some patients by inhibiting prostaglandin synthesis. Indomethacin may also affect plasma renin levels, aldosterone excretion, and renin profile evaluation. Patients receiving both indomethacin and Generic Lasix should be observed closely to determine if the desired diuretic and/or antihypertensive effect of Generic Lasix is achieved.

 

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